Objective To construct and apply the quality index system of preventive nursing of delirium in adult patients in ICU,so as to provide reference for the objective evaluation of the quality of preventive nursing of delirium in adult patients in ICU. Methods Based on the three-dimensional mass structure theory,the quality indicators and weights of delirium prevention care in adult patients in ICU were determined by literature research,qualitative interviews,Delphi correspondence and analytic hierarchy. Preliminary application of the application checklist through qualitative interviews. Results Two rounds of expert correspondence were conducted,the positive coefficients of the two rounds of expert consultation were 100% and 86%,the authority coefficients were 84% and 82%,and the Kendall coordination coefficients were 0.154 and 0.187,respectively. The final quality index system of preventive care for adult patients with delirium in ICU includes 3 first-level indicators,13 second-level indicators and 71 third-level indicators. 100% of ICU medical staff are satisfied with the content of the checklist formed,and believe that it is representative and professional,and has clinical practicability. Conclusion The quality index system of preventive nursing of delirium in adult patients in ICU is scientific,rigorous and reliable,and can effectively evaluate the nursing quality of delirium prevention in adult patients in ICU.

Objective To observe the effectiveness of umbilical moxibustion treatment in patients with tumor targeted drug-related diarrhea. Methods 68 patients were divided into an observation group of 34 cases and a control group of 34 cases by sealed envelop method. The control group was given one bag of montmorillonite powder and 420mg of Bifidobacterium triple viable enteric coated capsules ,Take each orally with warm water,three times a day. The observation group received umbilical moxibustion treatment on the basis of the control group, once a day for five-cone each time. Both treatment groups have a duration of 2 weeks. comparing the stool frequency, stool consistency, and quality of life（evaluated by KPS score） between two groups of patients before and after treatment. Results After treatment, both groups of patients had a decrease in stool frequency, improvement in stool consistency, and improvement in quality of life. The observation group showed better efficacy than the control group （P<0.05）. Conclusion Umbilical moxibustion can effectively improve the stool frequency, stool consistency, and quality of life of patients with diarrhea caused by tumor targeted drugs.

Objective To explore the application effect and value of bronchoscopic alveolar lavage in children with severe Mycoplasma pneumoniae pneumonia. Methods 89 children with severe Mycoplasma pneumoniae pneumonia in the Department of Pediatrics of Meizhou People’s Hospital from January 2024 to March were selected and divided into group A （41 cases,conventional treatment） and group B （58 cases,conventional treatment+bronchoalveolar lavage）. The baseline data,clinical symptom relief time and hospitalization time of the two groups were compared. Results There were no significant differences in gender,age,duration of symptoms before admission （fever,cough,wheezing/shortness of breath）,oxygen partial pressure and lactic acid between the two groups（P>0.05）.There was no significant difference in fever disappearance time and cough recovery time between group A and group B （P>0.05）. The disappearance time of wheezing/shortness of breath in group B （1.42±1.11 vs 2.20±1.69） d was less than that in group A （P<0.05）. The length of hospitalization time in group B （6.00±1.09 vs 6.90±1.50）d was less than that in group A （P< 0.05）. Conclusion For children with severe mycoplasma pneumoniae pneumonia,bronchoalveolar lavage is effective,which can quickly relieve symptoms,promote recovery and shorten hospital stay.

Objective To observe the clinical effect and safety of oxaliplatin and irinotecan in the adjuvant treatment of CRLM. Methods A prospective clinical controlled trial was carried out in 112 patients with CRLM treated in our hospital from March 2023 to March 2024. After generating the random sequence by computer grouping method,the patients were divided into Oxaliplatin group and Irinotecan group,with 56 cases in each group. The Oxaliplatin group was treated with Oxaliplatin+Capecitabine combined with targeted therapy,and the Irinotecan group was treated with Irinotecan+Capecitabine combined with targeted therapy. The patients were followed-up for one year after treatment,and the short-term efficacy and prognosis of the two groups were compared. Results After treatment,the CR and PR of Oxaliplatin group were higher than those of Irinotecan group,and the SD and PD of oxaliplatin group were lower than those of irinotecan group （χ²=4.495,4.762,5.657,8.391;P<0.05）. The levels of CEA,AFP,CA199 and ctDNA in Oxaliplatin group were lower than those in Irinotecan group （t=3.051,3.348,3.207,11.687;P<0.05）. During the follow-up period,the Incidence of adverse reactions in Oxaliplatin group was 26.79% （15/56）,which was lower than 46.43% （26/56） in Irinotecan group （χ²=4.655;P<0.05）. By the end of follow-up,the survival rate,mPFS and mOS of the Oxaliplatin group were higher than those of the conventional group （χ²=4.323,3.261,3.244;P<0.05）. Conclusion Oxaliplatin+Capecitabine combined with targeted therapy is more conducive to improve the short-term efficacy and short-term prognosis of patients with crlm,its therapeutic effect and safety are better than that of Irinotecan,which has higher application value in the anti-tumor treatment of patients with CRLM.

Glucagon-like peptide-1（GLP-1）receptor agonists（GLP-1RAs）,emerging as a novel class of antidiabetic agents,have demonstrated substantial cardioprotective effects. Accumulating evidence suggests that GLP-1RAs mitigate ferroptosis in cardiomyocytes through modulation of key signaling cascades,including the AMP-activated protein kinase（AMPK） and nuclear factor erythroid 2-related factor 2（NRF2） pathways. This protective mechanism contributes to the amelioration of various cardiovascular pathologies,notably diabetic cardiomyopathy and myocardial ischemia-reperfusion injury. This paper systematically reviews the cardiovascular benefits of GLP-1 receptor agonists,the molecular mechanisms by which they inhibit ferroptosis in cardiomyocytes,and prospects for future research,aiming to provide new targets and strategies for the prevention and treatment of cardiovascular diseases.

Objective To reduce the rate of irrational use of proton pump inhibitors（PPIs）among inpatients. Methods A special review of PPIs used by hospitalized patients in 2024 was conducted,and the PDCA cycle management method was applied to improve the rationality rate of PPIs clinical application. Results A total of 729 PPIs inpatient cases were sampled in 2024. Through the PDCA cycle management method,the rate of qualified PPIs medical orders gradually increased from 73.33% in January to 93.98% in December. Conclusion The application of the Plan-Do-Check-Act（PDCA） cycle management method can effectively improve the rationality rate of PPIs clinical application in hospitalized patients.

With the continuous progress of medical technology and the increasingly stringent requirements of society on the quality of medical services,the pre-hospital emergency care has become more and more important in recent years,witch as a very important link in the healthcare service system. This paper mainly discusses the application and current situation of medical humanistic care in pre-hospital emergency care,analyzes the problems and challenges of humanistic care in pre-hospital emergency care,and puts forward the corresponding improvement measures,through the construction of a humanistic care system,in order to improve the quality of pre-hospital emergency care and provide patients with a more comprehensive,meticulous and humanistic care,so as to provide references for pre-hospital emergency care practice.

Objective This study aims to assess the prevalence and epidemiological characteristics of adolescent scoliosis in Shinan District,Qingdao City,through campus screening,explore the regional,gender,and grade characteristics of suspected scoliosis cases,and provide a scientific basis for improving the regional adolescent spinal health management system. Methods A cross-sectional study design was adopted. From September to December 2024,stratified random sampling was conducted in 28 primary and secondary schools in Qingdao City,covering 45612 students aged 6 to 16 years. The initial screening was conducted using the observation method,observing the height of both shoulders,the symmetry of the scapulae,the symmetry of the iliac crests,and the alignment of the spinal midline. Subsequently,the trunk rotation angle (ATR) was measured. Under the guidance of therapists,students performed the Adam’s forward bend test,and the Scoliometer was used to measure the rotation angles of each spinal segment. An ATR≥ 5° was set as the positive threshold. Data were statistically analyzed using SPSS 26.0 software. Normality was tested using the Shapiro-Wilk method. Categorical variables were expressed as frequencies (percentages). The χ² test was used to compare gender and regional differences,and analysis of variance (ANOVA) was used to evaluate differences in prevalence among grades. Results A total of 45612 students were screened,with a suspected scoliosis (ATR≥ 5°) detection rate of 4.82%. Among them,971 students in Shinan District had a suspected scoliosis rate of 4.42%,and 1227 students in Laixi City had a suspected scoliosis rate of 5.19%. The suspected scoliosis rate in Shinan District was lower than that in Laixi City (F = 14.970,P< 0.005). A total of 22479 girls and 23133 boys were screened. Among them,1388 girls and 810 boys were suspected of having scoliosis,with a suspected scoliosis rate of 6.17% for girls,significantly higher than 3.50% for boys (F = 19.329,P< 0.005). The suspected scoliosis rates for the sixth grade of primary school and grades one to three of junior high school were as high as 5.90%,5.90%,6.20%,and 7.30%,respectively. The suspected scoliosis prevalence in higher grades was significantly higher than that in lower grades (F = 23.276,P< 0.005). Conclusion Differentiated prevention and control of scoliosis in urban and rural areas,with a focus on screening resources in suburban areas such as Laixi (e.g.,portable electronic measuring devices),and the establishment of a “school-medical-home” referral network in collaboration with grassroots health centers to shorten the diagnosis and intervention cycle. Consider listing girls and junior high school students as key groups for scoliosis screening in regular physical examinations in Qingdao,and establish an integrated system of “screening-referral-intervention”.

Objective To explore the application effect of mixed teaching based on O-AMAS effective teaching model in chronic heart failure cardiac rehabilitation training course. Methods A total of 70 students rotated in the Department of Cardiopulmonary Rehabilitation from February 2023 to September 2024 were selected. They divided into control group and observation group by random number table method of 35 cases each . The control group adopted conventional teaching and the observation group adopted mixed teaching based on O-AMAS effective teaching model in failure cardiac rehabilitation training course. The students’academic performance,teaching cooperation and teaching satisfaction were compared between the two groups. Results The routine performance,theoretical scores and skill operation assessment scores of the observation group were higher than those of the control group （P<0.05）. The teaching cooperation of the observation group was better than that of the control group （P<0.05）. The teaching satisfaction of the observation group was higher than that of the control group （P<0.05）. Conclusion The application of mixed teaching on O-AMAS effective teaching model in heart failure cardiac rehabilitation training course has a significant effect. It can effectively improve the academic performance of students,and improve the cooperation and satisfaction of students in training teaching,which is worth of application and promotion.

Objective To analyze the efficacy of multi-slice spiral CT in the diagnosis of acute intestinal obstruction,and to observe the coincidence rate of multi-slice spiral CT in the judgment of the cause,nature and location of acute intestinal obstruction. Methods A total of 175 patients with intestinal obstruction admitted in our hospital from January 2021 to December 2024 were selected. After admission,all patients received multi-slice spiral CT examination before operation. The surgical pathological examination results were used as the gold standard,and the coincidence rate of multi-slice spiral CT examination in the degree,nature,etiology and location of intestinal obstruction was calculated. Result The total coincidence rate of MSCT in detecting the location of intestinal obstruction was 98.29% （172/175）. The total coincidence rate of MSCT in detecting the cause of intestinal obstruction was 97.71% （171/175）. The total coincidence rate of MSCT in detecting intestinal obstruction was 97.71% （171/175）. The total coincidence rate of MSCT in detecting the degree of intestinal obstruction was 98.29% （172/175）. Conclusion In the diagnosis of patients with acute intestinal obstruction,multi-slice spiral CT examination has high diagnostic efficacy,and has a high coincidence rate in the judgment of the location,nature,etiology and degree of intestinal obstruction.

Objective To explore the related influencing factors of radiation esophagitis（RE）in patients with esophageal cancer （EC） after radiotherapy,and to establish a regression equation to explore its predictive value,so as to provide reference for clinical rational formulation of preventive measures. Methods The clinical data of 202 patients with EC who underwent radiotherapy in Anyang Cancer Hospital from December 2022 to September 2024 were retrospectively analyzed. The patients were divided into RE group （63 cases） and non-RE group （139 cases） according to the occurrence of RE. The influencing factors of RE in EC patients after radiotherapy were analyzed by univariate and multivariate Logistic regression analysis. The regression equation was established,the likelihood ratio χ² was evaluated,the Hosmer-Lemeshow test was used to test the fitting degree,and the receiver operating characteristic curve （ROC） was drawn to obtain the area under the curve （AUC）. The predictive value of the regression equation for RE in EC patients after radiotherapy was analyzed. Results Multifactorial Logistic regression analysis showed that combined diabetes mellitus （OR=2.933,95%CI：1.822~4.772）,having hypoproteinemia （OR=1.093,95% CI：1.043~1.146）,combined hypertension （OR=2.779,95%CI：1.885~4.096）,the tumor location of the neck segment （OR=2.145,95%CI：1.380~3.333）,concurrent chemotherapy （OR=2.522,95%CI：1.661~3.829） and mean irradiation dose to target area ≥30 Gy （OR=1.102,95%CI：1.043~1.164） were independent risk factors for the development of RE after radiotherapy in EC patients （P<0.05）. The AUC value of the constructed regression equation for predicting the occurrence of RE after radiotherapy in EC patients was 0.855,with a 95% CI of 0.799~0.900,a sensitivity of 76.19%,and a specificity of 82.73%. Conclusion The occurrence of RE after radiotherapy in patients with EC were closely related to the combination of diabetes mellitus,hypoproteinemia,hypertension,tumor location in the cervical segment,concurrent chemotherapy,and an average irradiation dose to target area≥30 Gy. The regression equation established accordingly could better predict RE after radiotherapy in EC patients,which could provide reference for clinical decision-making.

Objective To study the clinical efficacy of electromyographic biofeedback,suspension training and Kegel exercise in the combined treatment of female stress urinary incontinence（SUI）. Methods The case data control analysis method was adopted. Data and information were entered starting from January 2021,and the data entry and comparative analysis were completed in June 2024. During the inclusion period,120 female patients confirmed with SUI were admitted as the basic sample. The groups were divided into the observation group and the control group by the coin-tossing method,with 60 patients in each group. Patients in the control group received Kegel exercise therapy intervention alone,while patients in the observation group received combined treatment of electromyogram biofeedback,suspension training and Kegel exercise. The clinical efficacy evaluation indicators included clinical effective rate,1-hour urine pad test,international Advisory Committee on Urinary Incontinence Questionnaire Scale Score（ICIQ-SF）,pelvic floor muscle strength indicators,and the incidence of adverse reactions. Results The clinical effective rate data of the observation group was significantly higher than that of the control group,and the differences were statistically significant （P<0.05）. After the treatment,the 1h urine pad test and ICIQ-SF score data of the observation group were significantly lower than those of the control group （P<0.05）,but the pelvic floor muscle strength index data of the observation group was significantly higher than that of the control group （P<0.05）. The comparison of the incidence data of adverse reactions between the two groups confirmed that there was no statistically significant difference （P>0.05）. Conclusion The combined treatment of electromyographic biofeedback,suspension training and Kegel exercise for female urinary incontinence （SUI） has a significant effect. It can reduce urine leakage,alleviate symptoms related to SUI,enhance pelvic floor muscle strength,and has a relatively high treatment safety.

Objective To explore the effect of Shengyang Chushi Formula in the treatment of patients with subacute eczema,and to analyze its influence on the skin physiological functions and inflammatory factors of patients. Methods A total of 98 patients with subacute eczema in our department from April 2023 to October 2024 were included as the research subjects. They were divided into 2 groups by random number table method,with 49 cases in each group. The control group received conventional western medicine treatment such as triamcinolone acetonide econazole cream and desloratadine Tablets, while the observation group was treated with Shengyang Deshi Formula in addition. Both groups were treated continuously for 3 weeks. The clinical efficacy,skin physiological function indicators（percutaneous water loss,stratum corneum water content,skin oil content）,inflammatory factors（EOS,IL-17）,recurrence rate and adverse reactions of the two groups were compared. Results After treatment,the recurrence rate of the observation group was lower than that of the control group,and the total effective rate was higher than that of the control group （P<0.05）;The WCSC and SC of patients in the observation group were higher than those in the control group,and the TEWL was lower than that in the control group （P<0.05）. The EOS and IgE of patients in the observation group were both lower than those in the control group （P<0.05）. There was no significant difference in adverse reactions between the two groups （P<0.05）. Conclusion The combination of Shengyang chushi Formula and western medicine in the treatment of patients with subacute eczema has a remarkable effect. It can effectively alleviate the skin allergic reactions of patients,repair the skin barrier function of patients,and reduce the recurrence rate. It is worthy of clinical recommendation.

Objective To analyze the influencing factors of psychosocial adaptation in patients with colorectal cancer undergoing permanent colostomy and explore feasible intervention measures. Methods A total of 99 patients who underwent permanent colostomy for colorectal cancer from February 2023 to February 2025 in our Hospital were selected as the study subjects. The general data of the patients were collected,and the scores of Chinese version of the Ostomy Adjustment Inventory （OAI）,Medical outcomes study social support survey （MOS-SSS）,Mishel's Uncertainty in Illness Scale （MUIS）,the self-management questionnaire for colostomy patients,and Patient-Generated Subjective Global Assessment （PG-SGA）scale were investigated to evaluate the level of social psychological adaptation,the degree of medical social support,the uncertainty in illness,the self-management ability and the nutritional status of the patients,respectively. The OAI scores of patients with different clinical characteristics were compared,and multiple linear regression analysis was used to analyze the influencing factors of OAI scores in patients with permanent colostomy for colorectal cancer. Results In this study,99 questionnaires were distributed and 98 were recovered,with an effective recovery rate of 98.99%. The psychosocial adaptation score of 98 patients with colorectal cancer after permanent colostomy was （44.21±5.02） scores,including 30 cases （30.61%） of low level,57 cases（58.16%）of medium level and 11 cases（11.22%） of high level. There were statistically significant differences in the OAI scores of patients with colorectal cancer after permanent colostomy with different educational levels,payment methods,PG-SGA scores,stoma complications,MUIS scores,self-management questionnaire scores of patients with colostomy,and MOS-SSS scores （P<0.05）. The results of multiple linear regression analysis showed that stoma complications,PG-SGA score,MUIS score,self-management questionnaire score of patients with colostomy and MOS-SSS score were the influencing factors of psychosocial adaptation in patients with colorectal cancer after permanent colostomy （P<0.05）. Conclusion The influencing factors of psychosocial adaptation in patients with colorectal cancer after permanent colostomy include nutritional status,self-management ability,stoma complications,disease uncertainty,medical and social support. Therefore,clinicians can try to combine multiple resources to carry out clinical nursing,and improve the level of psychosocial adaptation and prognosis of patients by strengthening knowledge education,reasonable nutritional support and other targeted measures.

Objective To analyze the correlation between the types of mycoplasma and chlamydia genital tract and cervical mucus inflammatory factors in female infertility patients. Methods 120 female infertility patients were prospectively selected from January 2022 to November 2024 at our hospital,and baseline data were collected. Multivariate linear regression was employed to analyze the influencing factors of tumor necrosis factor-α（TNF-α）and interferon-γ （IFN-γ）in these patients. The study further examined correlations between Mycoplasma positivity status,Chlamydia positivity status,Mycoplasma species,Chlamydia species,and both TNF-α and IFN-γ levels. Results In this study,120 female infertility patients had mycoplasma and chlamydia infections in 68 cases with infection rate of 56.67%,the positive composition ratio of mycoplasma in infection mode was 66.18%（45/68）,the positive composition ratio of chlamydia was 14.70%（10/68）,and the mixed positive composition ratio was 19.12%（13/68）. Among them,82 pathogens were detected in infected patients,67 mycoplasma strains （81.71%）,Uu （56.10%） had the highest proportion,and 15 strains of chlamydia Ct （18.29%）. The results of univariate analysis showed that infertility types,vaginal microecological imbalance and infection types were significantly different between TNF-α and IFN-γ （all P<0.05）. The results of multiple linear regression analysis showed that the type of infertility （secondary）,vaginal microecological imbalance and infection type （Uu,Mg,Mh,Ct and mixed infection） were independent influencing factors of TNF-α and IFN-γ in female infertility patients （all P< 0.05）. Conclusion The main pathogen infection in female infertility patients is mycoplasma. The types of infertility （secondary）,vaginal microecological imbalance,and infection types （Uu,Mg,Mh,Ct and mixed infections） are related to the levels of inflammatory factors in cervical mucus of female infertility patients. We especially need to closely monitor such patients and personalized plan,in order to promote female reproductive health.

Objective With the rapid development of the social economy and the continuous improvement of people’s living standards,public awareness of life and health has been increasingly heightened. However,the incidence of emergencies and accidental injuries has also risen annually. As a critical component of hospital medical services,pre-hospital emergency care carries inherent medical risks when managing critically ill patients. Insufficient understanding of diseases,improper management,and other factors may lead to adverse outcomes for patients during pre-hospital emergency procedures. In recent years,medical disputes have shown an upward trend,yet their resolution often remains unsatisfactory. Therefore,effectively preventing medical disputes,improving healthcare quality,enhancing service awareness,standardizing professional practices,and reducing conflicts have become essential tasks in pre-hospital emergency care. This study analyzes problems encountered in pre-hospital emergency care and causes of medical disputes,proposing corresponding countermeasures.

Objective Professor Qi Yuanfu is good at applying antipyretic and detoxifying Chinese medicines in the clinical treatment of lung cancer,and under the guidance of Fuzheng Guben Thought,dialectically applies antipyretic and antidote drugs according to the different stages of the patient’s disease,treatment stage and personal physical condition,so as to achieve the effect of both supporting the right and dispelling evil. It reflects the clinical value of antipyretic and detoxifying traditional Chinese medicine in the treatment of lung cancer in traditional Chinese medicine.

Objective To observe the application effect of Stereotactic Radiosurgery（SRS）on patients with glioma. Methods A prospective clinical controlled trial was conducted on 120 patients with glioma in our hospital from January 2023 to June 2024. After generating random sequence by computer grouping method,the patients were divided into conventional group and minimally invasive group,with 60 cases in each group. The conventional group received conventional craniotomy for glioma resection,and the minimally invasive group received SRS treatment. The patients were followed-up for half a year. The clinical indicators,blood-brain-barrier function,neurological function and complications of the two groups were compared. Results Under different treatment schemes,the operation time,anesthesia time,intraoperative blood loss,ICU stay time,ambulation time and hospitalization time of the minimally invasive group were lower than those of the conventional group （t=14.227,16.935,43.983,12.804,16.160,4.789;P< 0.05）. The MMP9 in the minimally invasive group was lower than that in the conventional group,Occludin（OCLN）,Zonula Occludens1（ZO-1）,CTⅣ was higher than that of the conventional group （t=3.486,2.710,3.152,3.434;P< 0.05）. The levels of GFAP,NSE,NF-L and S100 β in the minimally invasive group were lower than those in the conventional group （t=15.257,3.423,3.533,2.578;P< 0.05）. By the end of follow-up,the incidence of complications in the minimally invasive group was 8.33% （5/60）,which was lower than 23.33%（14/60）in the conventional group （χ²=5.065;P< 0.05）. Conclusion SRS can improve the operation efficiency of patients with glioma,and accelerate the postoperative rehabilitation process of patients,which can effectively reduce blood-brain-barrier injury and nerve function injury,and also has a positive impact on reducing the risk of complications.

Objective To observe the application effect of Parks incision under a microscope in minimally invasive strabismus correction surgery for children. Methods A total of 125 children with strabismus admitted to our hospital from January 2022 to May 2024 were selected as the research subjects. Using the digital drawing method,63 children with odd numbers were selected as the experimental group,and 62 children with even numbers were selected as the conventional group. The conventional group received routine corneal incision strabismus correction surgery,while the experimental group received microscopic Parks incision strabismus correction surgery. After the treatment completed,a six-month follow-up was conducted to compare the clinical indicators,visual function,tear film function,and postoperative complications of the two groups of children. Results Under different treatment plans,the surgical time,incision diameter,intraoperative blood loss,and postoperative hospital stay in the experimental group were （20.35 ± 5.49）min,（6.45 ± 1.21）mm,（2.52 ± 0.36）mL,and （4.11 ± 1.36）d,respectively,all lower than those in the conventional group [（35.22 ± 5.37）min,（8.29 ± 1.47）mm,（3.37 ± 0.35） mL,and （5.66 ± 1.48）d] （t=15.306, 7.585, 13.382, 6.098; P< 0.05）. The strabismus degree of the experimental group （5.44 ± 1.29）^△ was lower than that of the conventional group （7.19 ± 1.88）^△,and the coincidence point of the same vision machine examination （18.66 ± 3.23） ° was higher than that of the conventional group （15.45 ± 3.12） ° （ t = 6.077,5.650;P<0.05）. The BUT and SIT of the experimental group were higher than those of the conventional group,and the CFS was lower than that of the conventional group （t=3.819, 5.135, 4.774; P< 0.05）. As of the end of follow-up,the incidence of complications in the experimental group was 7.94% （5/63） lower than that in the conventional group 19.35% （12/62）（χ² = 4.735;P<0.05）. Conclusion The Parks incision under the microscope has high application value in minimally invasive strabismus correction surgery for children,which has positive significance in improving surgical efficiency,reducing surgical risks,accelerating postoperative visual function recovery,avoiding tear film damage,and reducing the risk of postoperative complications.

Objective To explore the therapeutic value of deep puncture Nayang acupuncture combined with speech rehabilitation training on aphasia after stroke. Methods A total of 96 patients with post-stroke aphasia（all motor aphasia）who were diagnosed and treated in Nankai District Hospital of Traditional Chinese Medicine,Tianjin University of Traditional Chinese Medicine from Jan 2024 to Jan 2025 were selected and randomly divided into two groups. The control group （48 cases） was given speech rehabilitation training,and the experimental group（48 cases）was given deep puncture Nayang acupuncture combined with speech rehabilitation training. The disease-related scores,overall efficacy,cognitive function and adverse reactions after treatment were compared. Results At the end of the 4-week course of treatment,the scores of Chinese Aphasia Rating Scale（ABC）and Functional Language Communication Proficiency Test（CFCP）in the experimental group were higher than those in the control group. The total effective rate of the experimental group（93.75%） was higher than that of the control group （77.08%）. The scores of the Mini-Mental State Examination（MMSE）and Montreal Cognitive Assessment Scale（MoCA）were higher in the experimental group than those in the control group （all P<0.05）. There was no significant difference in the incidence of adverse reactions between the experimental group （8.33%） and the control group （4.17%） （P> 0.05）. Conclusion Deep puncture and speech rehabilitation combined with speech rehabilitation have a definite effect on aphasia after stroke,with good recovery of the patient's condition,can promote the improvement of cognitive function,and have a high safety profile.