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  • Expert Consensus on the Construction of a Model for Intracranial Monitoring System of Subarachnoid Hemorrhage Using New Materials and New Technologies
    Li Gen, Chen Jie, Miao Yan, Gou Guangyang, Zhuang Chengyu, Sun Xuan, Liu Chunxiu
    2024, 56(6): 401-406. https://doi.org/10.3969/j.issn.1006-5571.2024.06.001
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    Subarachnoid hemorrhage (SAH) is a cerebrovascular disease with a high mortality and disability rate. Its pathological mechanism is complex, and clinicalresearch faces challenges such as insufficient stability and low survival rate of animal models. This consensus systematically summarizes the limitations of traditional SAH animal models and proposes optimized modeling techniques, significantly improve model stability and reduce the mortality rate of experimental animals. At the same time, a multi-modal intracranial monitoring system is constructed by combining both multi-channel flexible sensors and 3D bioprinted scaffolds, achieving real-time dynamic monitoring of intracranial pressure, cerebral oxygen partial pressure, and brain electrical activity, promoting the regeneration and repair of cranial bone defects. The application of the new system provides a highly reliable platform for the analysis of SAH pathological mechanisms, the evaluation of new therapies, and the development of brain-computer interfaces. It is expected to promote the clinical transformation of brain-computer interface research results.
  • To explore the pathogenesis and intervention of sarcopenia from the perspective of gut-muscle axis
    Liao Junhua, Li Xiaoxin, Liao Yunyi, Liu Xinyi, Gong Siyu, Zhao Xiaoshan
    2024, 56(6): 407-412. https://doi.org/10.3969/j.issn.1006-5571.2024.06.002
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    Sarcopenia is an age-related disease that brings numerous adverse consequences to patients and imposes an economic burden on society. The gut-muscle axis, serving as a bridge between intestinal flora and muscle, holds the potential for treating sarcopenia. However, its mechanism remains unclear, and the effect of intervention on sarcopenia is still far from ideal. Therefore, this paper reviews the correlation between the gut-muscle axis and sarcopenia, the involvement of the gut-muscle axis in the pathogenesis of sarcopenia, and the intervention of the gut-muscle axis on sarcopenia. The results demonstrate that intestinal flora can influence muscle quality and function through protein synthesis and decomposition, mitochondrial function, oxidative stress, insulin resistance, and chronic low-grade inflammation, among others. Moreover, the combination of exercise and drugs, particularly in combination with intestinal flora butyrate, can yield a better therapeutic outcome for sarcopenia.
  • Influencing factors of care dependency in stroke patients:a systematic review
    Wang Junwei, Liu Xiujing, Ma Shasha, Yu Jiajia, Du Hongpeng, Xu Ning
    2024, 56(6): 413-419. https://doi.org/10.3969/j.issn.1006-5571.2024.06.003
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    Objective To systematically review the influencing factors of caring dependence in stroke patients, so as to provide a scientific basis for reducing caring dependence and improving the quality of life of stroke patients. Methods The literature on influencing factors of caring dependence in stroke patients from CNKI, Wanfang, VIP, CBM, CINAHL, Pubmed and other Chinese and foreign databases were searched from their inception to 30th July 2023. Literature screening strictly followed the inclusion and exclusion criteria, and two researchers independently extracted data and evaluated the quality of the included literature. The research was analyzed by Review Manager 5.4 and Stata 14.0. Results A total of 9 studies involving 2362 subjects were included. The AHRQ quality assessment scores of the papers ranged from 6 to 9. The results of the meta-analysis showed that age, limb dysfunction, coexisting with other chronic diseases, degree of depression, cognitive dysfunction, and rehabilitation self-efficacy were the main influencing factors of caring dependence of stroke patients. Conclusions Caring dependence is common in stroke patients, but the level is inconsistent, and there are many influencing factors involved. High-risk groups should be identified as soon as possible and targeted nursing intervention should be carried out.
  • Application of disposable flexible ureteroscope in primary ureteral lithotripsy
    Zhang Kaineng, Kui Mengxia, Wang Bin, Mai Xiao, Ke Changxing, Zhao Jinzhi
    2024, 56(6): 420-423. https://doi.org/10.3969/j.issn.1006-5571.2024.06.004
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    Objective To summarize the application of domestic disposable electronic ureteroscope in the primary treatment of renal or upper ureteral calculi. Methods From September to November 2022, clinical data from 100 patients with renal or upper ureteral stones treated at the Urology Department of Dali Bai Autonomous Prefecture People's Hospital were collected. These patients were treated with domestically produced disposable electronic flexible ureteroscopes. The analysis included surgical time, stone fragmentation time, postoperative hospital stay, postoperative stone clearance rate, Visual Analogue Scale (VAS) score, Comfort Criteria Scale (BCS) score, and complications. The ureteral soft lens sheath of F11hammer 13 or F12Compact 14 was implanted during the operation, and 365 μ m laser optical fiber combined with holmium laser lithotripsy was used. Double J tubes and urinary catheterization were routinely placed after operation. Results Lithotripsy was successfully completed in 94 patients, and ureteral stent was retained in 6 patients because ureteral stricture could not be inserted into ureteroscope sheath and lithotripsy failure. Operation time was 30~80min(48.02±12.53)min; holmium laser lithotripsy time was 18~65min (37.54 ±9.83) min; postoperative hospital stayed 1 to 6 d(2.24 ±0.94) d, postoperative infection in 2 cases (2.0%), VAS score was (1.86 ±1.05), BCS score was (1.74 ±0.44), The stone clearance rate was 85.1% (80/94) one month after surgery and 96.8% (91/94) three months after surgery. One patient with renal calculi appeared "stone street" after operation. In 2 patients, the infrarenal calyx neck was slender and the IPA angle was small,so soft lens could not completely enteredand lithotripsy failure. Conclusion Domestic disposable electronic ureteroscope is a minimally invasive, safe and effective method for one-stage treatment of renal and upper ureteral calculi (diameter < 2cm).
  • ROC curve analysis of the correlation between sex hormone levels and osteoporosis in perimenopausal women
    Xing Chengtao, Huang Jianian, Guang Bo, Qian Kun
    2024, 56(6): 424-427. https://doi.org/10.3969/j.issn.1006-5571.2024.06.005
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    Objective To explore the correlation analysis and predictive value of perimenopausal women's sex hormone level and osteoporosis. Methods Seventy cases of perimenopausal women with osteoporosis who came to our hospital from February 2023 to August 2024 were selected as the study group, and 70 cases of perimenopausal healthy women who came to our hospital for physical examination in the same time period were selected as the control group. Sex hormones [estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH)], bone metabolism indexes [N-terminal pro-peptide of pre-collagen type I (PINP), N-terminal osteocalcin (N-MID), and β-collagen degradation products (β-CTX)], and bone mineral density (BMD) levels were compared between the two groups. The correlation between sex hormone levels and osteoporosis was analyzed. Working characteristic curves of the subjects were plotted to assess the predictive efficacy of sex hormone levels for osteoporosis. Results Compared with the control group, the study group had lower levels of serum E2, lumbar spine BMD, femoral neck BMD, and hip BMD, and higher levels of FSH, PINP, N-MID, and β-CTX. Serum E2 was negatively correlated with the levels of PINP, N-MID, and β-CTX (r=-0.341, -0.470, and -0.538, all P<0.001), and positively correlated with the levels of lumbar BMD, femoral neck BMD, and hip BMD (r=0.579, 0.527, and 0.522, all P<0.001). Serum FSH was positively correlated with the levels of PINP, N-MID, and β-CTX (r=0.361, 0.368, 0.522, all P<0.001), and negatively correlated with the levels of lumbar BMD, femoral neck BMD, and hip BMD (r=-0.536, -0.552, and -0.541, all P<0.001). The AUCs of serum E2, FSH and their combination for predicting osteoporosis in perimenopausal women were 0.890, 0.894, and 0.960, with 95% CIs of 0.826~0.936, 0.831~0.940, and 0.912~0.986, respectively, with sensitivities of 84.29%, 80.00%, and 91.43%, and specificities of 78.57%, 82.86%, and 92.86%, respectively. Conclusion Sexual E2 and FSH levels in perimenopausal women are closely related to the occurrence of osteoporosis, and the combination of the two is highly effective in predicting osteoporosis, which has good clinical application value.
  • Investigation of depression status and related factors in patients with postoperative chemotherapy for gynecologic malignant tumors
    Gao Zubiao, Zhang Cuirun, Tan Cuixing, Ye Minting, Chen Jiexiang
    2024, 56(6): 428-432. https://doi.org/10.3969/j.issn.1006-5571.2024.06.006
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    Objective To study the results of the survey on depression status and related factors for patients of gynecologic malignant tumors undergoing postoperative chemotherapy. Methods 108 patients with gynecological malignant tumors (including cervical cancer, endometrial cancer, ovarian cancer) postoperative chemotherapy in our hospital from July 2022 to June 2024 were random sampling prospectively selected as the object of observation, investigation and comparison of the two groups of general information, analysis of the correlation between the total score of social support, family functioning and the correlation between the scores of the dimensions and the scores of the depression scale, and the factors affecting the patient's depressive status was analyzed. Results The results of the investigation showed that 58 patienrs were depressed, which were recorded as the observation group, and 50 patients were not depressed, which were recorded as the control group. In the observation group, the proportion of patients with high school education and above, economic income<3000 yuan/month, disease stage III-IV, the number of times they received health guidance from healthcare personnel <3 times was higher than control group, and the score of depression scale were higher than that of the control group, and the score of family caring index and social support were lower than that of the control group (P<0.05). Evaluation using Pearson's correlation analysis found that the total score of social support, family functioning and scores of each dimension was negatively correlated with depression scale score (P<0.05). According to logistic regression analysis, it was found that the education level of high school and above, economic income <3000 yuan/month, disease stage III-IV, the number of times of getting health guidance from medical staff <3 times, the family care index and social support score were the influence factors for patients' depression (OR>1, P<0.05). Conclusion There is a certain depression condition in patients with gynecologic malignant tumors treated with postoperative chemotherapy, and there are more factors affecting patients' depression,witch needs clinical attention.
  • BRAF (V600E) gene mutation in 449 patients with thyroid nodules by fine needle puncture biopsy
    Xu Huijuan , Sun Qi, Liu Kun, Luo Ruichen, Chen Huan, Huang Ying, Hou Jun
    2024, 56(6): 433-437. https://doi.org/10.3969/j.issn.1006-5571.2024.06.007
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    Objective To study BRAF gene mutation in patiens with fine needle aspiration (FNA), and the clinical value of fine needle aspiration-combined with BRAF V600E gene detection in diagnosing the thyroid and BRAF combined detection in diagnosing the benign and malignant nature of nodules. Methods The date of499 patients with thyroid nodules performed cytological test by FNA in Zhongshan Hospital, Fudan University(Xiamen Branch) from January 2022 to May 2024 were collected. The BRAF gene was detected by real-time fluorescence quantitative PCR, and the BRAF(V600E) mutation was analyzed in 499 patients. Results Out of 449 patients, 255 tested positive for the BRAF(V600E) mutation, resulting in an overall positivity rate of 56.79%. Among them, the positivity rate among male patients was 71.82%, while that among female patients was 54.57%. Within the cohort of 255 BRAF(V600E) mutation-positive patients, cytology examination indicated malignant tumors in 54.12% of cases, Suspicious for malignancys in 30.20% of cases, and Atypia of undetermined significance in 13.33% of cases. Additionally, 1.57% of specimens were either Nondiagnostic; only a small proportion (0.39%) exhibited in Patients with follicular tumors/suspected follicular tumors or benign lesions.In this study, 170 patients was administered surgical treatment at our hospital. The postoperative pathological examination of BRAF(V600E) mutation-positive nodular puncture patients showed that the specific pathological type was papillary carcinoma,and the specificity was 100%. Conclusions BRAF (V600E) mutation detection plays a crucial role in in diagnosing the benign and malignant nature of nodules, complementing fine-needle aspiration cytology examination. The combination of these two methods can significantly improve the diagnostic specificity against benign and malignant thyroid nodules, thereby help patients develop a more precise treatment plan.
  • The Construction of Admission and Competency Evaluation Indicator System for Internet Plus Home Nursing Service Providers
    Zhang Ying, Xiong Yinhuan, Cui Kai, Dong Yameng, Shu Liping, Jiang Rongjun
    2024, 56(6): 438-442. https://doi.org/10.3969/j.issn.1006-5571.2024.06.008
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    Objective To construct the entry standards and job competency evaluation index system of online appointment nurse, providing reference for the selection and evaluation of online appointment nurse. Methods Based on the theory of competency iceberg, the evaluation index system was formulated by using the methods of literature research, group discussion, and Delphi expert inquiry. The weights of each index were determined by the analytic hierarchy process. Results Two rounds of expert inquiry were conducted, with positive coefficients of 100% for both rounds. The authority coefficients were 0.83 and 0.84, the consistency coefficients were 0.214 and 0.256, Finally a competency evaluation index system for online appointment nurse was constructed, including 4 entry standards, 4 first-level indicators, 12 second-level indicators, and 47 third-level indicators. Conclusion The construction of the entry standards and job competency evaluation index system for online appointment nurse is scientific and reliable, providing reference for the entry, training, and evaluation of internet-based nursing appointment in China.
  • Comparison of the clinical efficacy of surfactant in combination with NIPPV, HHFNC and NCPAP in the treatment of neonatal respiratory distress syndrome
    Cui Zhiliang, Ao Liyun, Song Zhongfu, Yang Jiachen, Zhang Jun, Zhu Xuliang
    2024, 56(6): 443-446. https://doi.org/10.3969/j.issn.1006-5571.2024.06.009
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    Objective To explore the clinical efficacy of pulmonary surfactant (PS) with intermittent positive nasal pressure ventilation (NIPPV), warmed and humidified high-flow positive nasal pressure ventilation (HHFNC) and nasal pronged continuous positive airway pressure (NCPAP) in the treatment of neonatal respiratory distress syndrome (NRDS). Methods A total of 90 preterm infants with NRDS curatived to our hospital from May 2022 to May 2024 were selected as the study subjects, and they were divided evenly into three groups according to the random number table method. The NIPPV group was treated with NIPPV, the HHFNC group was treated with HHFNC, and the NCPAP group was treated with NCPAP. Blood gas indexes, oxygen therapy, invasive ventilation and complications were compared between the three groups. Results There was no significant difference in blood gas indexes between the three groups at 0 h and 48 h (P>0.05), PaO2 and PaO2/FiO2 in the NIPPV group were higher than those in the HHFNC group and NCPAP group at 12 h, PaCO2 was lower than that in the control group, PaO2 and PaO2/FiO2 were higher and PaCO2 were lower in the NIPPV group and HHFNC group than those in the NCPAP group at 24 h (P<0.05). The duration of non-invasive ventilation was statistically shorter than that of the HHFNC group and the NCPAP group (P<0.05), and the rate of invasive ventilation and complications in the NIPPV group and HHFNC group were lower than those in the NCPAP group (P<0.05). Conclusion NIPPV treatment of NRDS can improve blood gas indexes faster, shorten the duration of oxygen therapy and non-invasive ventilation, and reduce the rate of invasive ventilation, which is safe and reliable.
  • Research on the needs of psychological crisis of students in higher vocational colleges and its intervention countermeasures
    Yuan Kaige, Zhang Jian, Wu Kangli, Zheng Yunliang
    2024, 56(6): 447-451. https://doi.org/10.3969/j.issn.1006-5571.2024.06.010
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    In recent years, the psychological problems of vocational college students have shown an upward trend, and campus psychological crisis events occur frequently. Psychological crisis intervention, as a key and difficult point in the mental health work of vocational colleges, faces new tasks and challenges. The article adopts a questionnaire survey method to conduct a sampling survey on the psychological crisis needs of students in a vocational college in Tianjin, aiming to understand the current situation, influencing factors, and students' needs for psychological crisis intervention that affect the occurrence of psychological crises among college students. This provides strong support and scientific basis for vocational colleges to carry out psychological crisis warning work, improve psychological crisis intervention mechanisms, and enhance the effectiveness of psychological crisis intervention.
  • Study on the effectiveness of vitamin D supplementation and height growth in prepubescent children
    Liu Fangyi, Ke Xiaosheng, Lin Liping, Wu Song, Ouyang Yafang
    2024, 56(6): 452-455. https://doi.org/10.3969/j.issn.1006-5571.2024.06.011
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    Objective To explore the effectiveness of vitamin D (VD) supplementation and height growth in prepubescent children. Method 330 prepubescent children who underwent height promotion at Jinjiang Hospital from June 2021 to June 2023 were selected and divided into three groups based on their VD levels: sufficient group, insufficient group, and deficient group, with 110 cases in each group. According to the guidelines, the sufficient group should be given 400 units of VD orally per day, the insufficient group should be given 800 units of VD orally per day, and the deficient group should be given 2000 units of VD orally per day for 3 months before switching to 800 units of VD orally per day. Record the height, weight, rate of motor dysfunction, rate of short stature, bone density, and serum 25 hydroxyvitamin D [25 (OH) D] of the enrolled subjects. The results showed that before treatment, the height, weight, and bone density of the sufficient group were higher than those of the insufficient group and the deficient group, while the rates of motor dysfunction and short stature were lower than those of the insufficient group and the deficient group. However, the height, weight, and bone density of the insufficient group were higher than those of the deficient group, while the rates of motor dysfunction and short stature were lower than those of the deficient group, with statistical differences (P<0.05); There was no statistically significant difference (P>0.05) in height, weight, 25 (OH) D, bone density, and rates of motor dysfunction and short stature among the three groups after VD supplementation. Conclusion VD supplementation in prepubescent children can effectively promote height growth, increase weight, improve bone density, and reduce the rates of motor dysfunction and short stature.
  • Evaluation of Immunotherapy Efficacy and Prognosis in Advanced and Recurrent Cervical Cancer Using Peripheral Blood T Cells and Tumor Markers
    Cui Xiaoli, Wu Wenli, Sui Lei, Luan Zhaohui, Sun Li
    2024, 56(6): 456-462. https://doi.org/10.3969/j.issn.1006-5571.2024.06.012
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    Objective By examining the changes of peripheral blood T lymphocyte subsets and tumor markers indexes before and after immunotherapy for advanced and recurrent cervical cancer, the correlation with therapeutic effect and prognosis was evaluated. Methods Fifty patients with advanced and recurrent cervical cancer who received first-line immunotherapy combined with chemoradiotherapy in Qingdao Central Hospital and partner hospitals from August 2022 to August 2024 were prospectively included. Detect the baseline level of patients before treatment and the expression rate of T lymphocyte subsets and Programmed death receptor-1 (PD-1) in 1 cycle after treatment. Combined with tumor markers squamous cell carcinoma antigen (SCC) and Carbohydrate antigen 125 (CA125), the influencing factors of efficacy were analyzed by Logistic regression. Cox regression was used to investigate the prognostic factors. Results Logistic regression showed that baseline CD4+T cell percentage, CD8+T cell percentage, CA125 and SCC, CD4+PD-1 and CD8+PD-1 expression rate after 1 cycle of treatment were the influencing factors of curative effect (P<0.05). Cox regression analysis showed that the percentage of baseline CD4+T cells, the percentage of CD4+T cells and CD8+T cells, the expression rate of CD4+ and CD8+PD-1, CA125 and SCC were prognostic factors. Conclusion The high percentage of CD4+T cells at baseline, the high percentage of CD4+T cells and CD8+T cells, the low expression rate of CD4+PD-1 and CD8+PD-1, and the low level of CA125 and SCC after 1 cycle of treatment may be favorable factors for patients to benefit from immunotherapy.
  • Analysis of influencing factors of complications after CT-guided percutaneous biopsy needle biopsy
    Zhou Fengnan, Lian Yanbang, Peng Xia, Wang Jie, Yuan Luna
    2024, 56(6): 463-467. https://doi.org/10.3969/j.issn.1006-5571.2024.06.013
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    Objective To investigate the influencing factors of complications after CT-guided percutaneous biopsy needle aspiration biopsy. Methods A total of 98 patients who underwent CT-guided percutaneous biopsy needle puncture biopsy at the First Affiliated Hospital of Zhengzhou University and 154th Hospital of Xinyang City from January 2022 to December 2023 were enrolled, . The incidence of complications after CT-guided split biopsy needle puncture biopsy was analyzed, and investigated its influencing factors and risk factors. Results All patients were successfully punctured, and 51 of 98 patients had complications, including 21 patients with postoperative hemoptysis, accounting for 21.43%, and 30 patients with pneumothorax, accounting for 31.62%. Patients with hemoptysis showed improvement after treatment with hemostasis drugs, and patients with moderate pneumothorax showed improvement after partial gas extraction. Patients with mild symptoms were relieved after bed rest. The incidence of pneumothorax and hemoptysis after CT-guided split biopsy needle biopsy was significantly related to the distance of the lesion from the chest wall, puncture times and puncture time (χ2=10.024, 7.078, 4.703, 7.564, 7.908, 7.356, all P<0.05). (χ2=10.024, 7.078, 4.703, 7.564, 7.908, 7.356, all P<0.05). Multivariate Logistic regression analysis showed that the risk factors for complications after CT-guided split biopsy needle biopsy were distance between focus and the chest wall, puncture times, and puncture time (OR=6.203, 6.653, 6.153, all P<0.05). Conclusion The main complications after CT-guided split biopsy needle biopsy are pneumothorax and hemoptysis, and the risk factors are the distance between focus and the chest wall, the number of puncture times and puncture time, Clinical prevention measures could be taken accordingly to reduce the incidence of complications.
  • Analysis of competency-oriented clinical skills training mode for postgraduate students in anesthesiology
    Xu Yongsheng
    2024, 56(6): 468-471. https://doi.org/10.3969/j.issn.1006-5571.2024.06.014
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    With the rapid development of global medical technology and the constant change of medical environment, medical education faces unprecedented challenges and opportunities. Especially in the field of anesthesiology, with the increase of the complexity of surgery and the diversification of patient needs, higher requirements are placed for the professional skills and comprehensive qualities of anesthesiologists. Therefore, the reform of medical education is imperative,Particularly, the ability-oriented training mode has become an important development trend of master's education in anesthesiology because it can effectively improve their clinical practice ability and the ability to adapt to the future medical needs. This paper aims to explore how to construct and implement a competency-oriented clinical skills training model to enhance clinical competence through in-depth analysis and review of the existing literature. By comparing and analyzing the training models in different countries and summarizing the successful cases and challenges, this paper will provide scientific basis and practical guidance for the reform of anesthesiology education, and help to cultivate more anesthesiology professionals with high-level clinical skills and professional qualities, so as to meet the growing demand for medical and health services.
  • Research on the Social First Aid System in Qingdao City
    Wang Yujun
    2024, 56(6): 472-476. https://doi.org/10.3969/j.issn.1006-5571.2024.06.015
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    Objective To summarize the building experience of the construction of the social emergency system in Qingdao, and provide countermeasuremeasures s for promoting the constructiondevelopment of the "big emergency" system and implementing the "healthy Qingdao" strategy. Method This paper GeneralizeSummarize and summarizes the experience of social emergency training ,of Qingdao's social emergency system, introduces the formation and deployment of volunteer teams, the construction of rural medical emergency linkage, and the construction of 120 AED electronic map. Results Qingdao The municipal government has attached importancepaid attention to the first aid training and assessment of the public, introduced the "Internet plus" information technology through the "Save Around" first aid volunteer service project, actively guided volunteers to participate in pre- hospital first aid work, and effectively improved the construction of social first aid system. Conclusion Qingdao has initially established a social emergency system, but there are still many weak linkssome weak points. It is necessary to further promote social emergency legislation, establish a social supporn t emergency incentive and guarantee mechanism, strengthen homogeneous and standardized social emergency training and management, expand the recruitment and training of emergency volunteers, improve the configurationallocation of urban AED and other emergency facilities, cultivate a good social emergency cultural atmosphere through multiple channels, encourage widespread public participation, and ensure the healthy and orderly development of the social emergency system.
  • Meridian flow theory at selected time auricular point pressure combined with acupressure for insomnia in patients with tuberculosis Intervention study of heart and spleen deficiency type
    Sun Shengming
    2024, 56(6): 477-480. https://doi.org/10.3969/j.issn.1006-5571.2024.06.016
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    Objective To observe the clinical effect of meridian flow theory at selected time and auricular point compression combined with acupressure on insomnia in tuberculosis patients (heart and spleen deficiency type). Methods 72 patients who met the criteria were divided evenly into observation group and control group according to the random number table method.The observation group was guided by the meridian flow theory to implement the timing auricular point sticking combined with acupressure treatment, while the control group performed the same treatment outside the meridian flow time. The PSQI scale, TCM symptom score and clinical efficacy of the two groups were observed before and after intervention. Results The total scores of PSQI and TCM symptoms and all the single observation indexes of the two groups were descend after treatment, with the statistically significant difference (P<0.05). The observation group had obvious advantages in sleep quality, sleep time, sleep efficiency and PSQI total score (P<0.05), and the observation group had outstanding curative effect on sleep difficulty, wakefulness, fatigue, dizziness and total score of symptoms of traditional Chinese medicine (P<0.05). The effective rate of observation group was higher than that of control group (P<0.05). Conclusion meridian flow theory at selected time and auricular point compression combined with acupressure can effectively improve the sleep quality of patients with tuberculosis insomnia (heart and spleen deficiency type).